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| See here. |
If you are interested and meet the criteria, I'd be happy to talk. I have some ideas that lean into the materials for electronics direction, and other possibilities are welcome.
A blog about condensed matter and nanoscale physics. Why should high energy and astro folks have all the fun?
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| See here. |
If you are interested and meet the criteria, I'd be happy to talk. I have some ideas that lean into the materials for electronics direction, and other possibilities are welcome.
It's that time of year yet again. The physics Nobel will be announced next Tuesday, and the chemistry prize on Wednesday. Who will it be this time? Please speculate in the comments. As is my annual futile tradition, I will put forward that the physics prize could be Aharonov and Berry for geometric phases in physics (even though Pancharatnam is intellectually in there and died in 1969). This is a long shot, as always, especially since last year's prize for “for the discovery of macroscopic quantum mechanical tunnelling and energy quantisation in an electric circuit” was condensed matter related. Perhaps optical metamaterials, with Yablonovitch, Smith, and Pendry? (Though that's another one where picking just three names is challenging.) Astro-related is likely due, so perhaps something CMBR related?
Several science items of interest from recent weeks. As always, apologies for missing some, which I'm sure to have done.
Last week the NSF issued a new memorandum describing the changes that they plan to make in agency programs and operations to implement the Golden Age of Science ideas advocated by the White House Office of Science and Technology Policy. It has been reported (Science, Nature) that many scientists are concerned about what is in the memo. The first words of the Science article: “For many U.S. scientists funded by the National Science Foundation (NSF), the agency they know and loved died on 10 September.” I will try to lay out why some people feel that way.
The memo outlines changes to operations that will fundamentally alter the character of the agency. Generally most of the ideas are not a priori bad if the agency were in an environment with greater resources, when experimentation with alternative funding schemes and evaluations was not a less-than-zero-sum proposition. Instead, these ideas are being put forward at a time when the NSF is underspending (for no obvious reason by the non-technical people in leadership roles) its appropriation for FY26 by around 18%. This self-imposed budget austerity takes a bad situation (great uncertainty for everyone, drastically reduced staffing, delayed/eliminated/consolidated programs) and makes it considerably worse. Now this memo outlines plans to take resources away from historically core programs and redirect them to new, untested initiatives, and to do so in ways that don’t always seem internally consistent.
The memo talks about trying to fund certain investigators for longer periods (e.g. five-year awards) with minimal goal direction (so that PIs are free to explore where ever the spirit moves them – across all of NSF’s portfolio, or only in chosen administration priority areas?), but there is no adequate discussion of how those people will be chosen. At the same time, there is talk of “golden tickets”, where individual reviewers in an already stripped-down review process can earmark some proposals for elevation, again with little explanation of how this will work. Without careful safeguards, this combination seems problematic, and the assertion that this will lead to higher risk/higher reward research unsupported. The memo also talks about short-duration, small budget awards for really risky proof-of-concept ideas. This isn’t crazy and the EAGER program has been good, but the idea that the key to enabling success in high-risk research is to reduce the budget and the timeline doesn’t make much sense to me.
There is a through-line that the agency is trying to treat workforce development as separate and distinct from funding research projects. As the Science article says, “Traditionally, most graduate students and postdocs are funded through a research grant to their adviser or lab chief. But that will no longer be the case. Instead, the memo says, ‘Talent development funding opportunities may be coordinated with [research]-focused activities, as appropriate, but will be distinct and goal-oriented efforts.’” The memo mentions nurturing talent through the NSF Graduate Research Fellowship program and proudly talks about how this was just renewed. What it doesn’t tell you is that it was renewed at a considerably lower level than in previous years, which seems completely at odds with the claim of bolstering the program. Similarly, the memo talks about expanding access to shared infrastructure like cleanrooms, etc., but stated targeted funding levels of programs like the NQNI are no higher now than they were 12 years ago, not even accounting for inflation. (I assume they will actually make NQNI awards.) If NSF leadership keeps slashing their own budget, in defiance of congressional appropriations, it won’t matter what their priorities are.
Lastly, let’s talk about “metascience”, the comparative study of different research funding models and practices, with the goal of a “self-improving NSF”. Again, the essential idea of doing careful studies of alternate funding mechanisms and research team structures and practices to improve research outcomes (not a trivial matter to define) is not bad. Doing this well is hard, because of several obvious reasons: How do you define successful research – by scholarly impact, by patents/economic impact, by production of educated scientists, some weighted average of these? On what timescale do you do this evaluation? The Einstein-Podolsky-Rosen paper was hardly cited for decades, and it is now arguably one of the most influential papers of the last hundred years, with enormous impact on quantum science and technology. How do you have sufficiently large samples and sufficiently long constant overall conditions to get reasonable statistics? There are strong practitioners of metascience out there, but when the memo says “These efforts ultimately serve a concrete ambition for NSF to double the scientific productivity and impact generated by each federal research dollar by 2036”, how can one take that seriously? No definitions of productivity or impact, and an implication that there will be optimization and major programmatic changes within less than two cycles of the much-vaunted five-year grants? The word “ambition” is doing all the work in that sentence.
Oh, and while all this is going on, the agency (among others) has now eliminated language from its integrity policy that used to say that political interference in grants and operations is bad. I’m sure that’s nothing to worry about.
There is tremendous uncertainty in funding from multiple agencies these days, and this has resulted in many universities cutting back on doctoral admissions in the sciences and engineering. This guarantees that there will be fewer PhD recipients in a few years across these disciplines. The large majority of PhDs in these areas do not go into academia and instead have formed the base of technical knowhow across diverse sectors of the US and global economy for decades. Cutting the supply like this will definitely have long-term consequences beyond just the halls of academia, affecting US competitiveness in ways that will take years to unravel. Adding to this uncertainty is not helpful to anyone.
This past week we launched SCOPE, a new center for science communication and public engagement. We marked the occasion with a fun symposium, as well as a Science Café event the preceding evening and a public science openhouse yesterday. The symposium was very enjoyable, with a panel that comprised Kelly Weinersmith (known for many things, including an outstanding podcast and popular science books such as this Hugo-award-winner), Peter Hotez (tireless champion of vaccine development and pushing back on disinformation), Eric Berger (space editor for Ars Technica, founder of spacecityweather and theeyewall, two excellent sites for no-hype weather information), and Briana Rapini (one of The Amoeba Sisters, creators of a youtube channel with 2.9M+ followers).
You might have picked up from my 21 years of blogging that I think science communication is of great importance. We've learned amazing things about how the world works, and I think we'd all be better off if more people knew about them and about the process of learning and discovery. If there is public investment in research, then it's incumbent upon researchers to make sure that the public has the opportunity to learn about the fruits of those labors. When the government, NGOs, and corporations make policies and strategic decisions that involve or depend on technical knowledge, we need to do our best to help those be informed decisions. Once upon a time, Congress had a research office to help their staff and office holders understand technological issues. It was killed in 1995 as "wasteful" and allegedly partisan. <sarcasm> thank goodness no technology-oriented issues have come up before the US government since then.</sarcasm> (I am very tired of victim-blaming that presents mistrust of science or partisan razing of the research ecosystem as somehow the direct fault of scientists who failed in the communication mission. Communication could have been better about many things, but complex societal forces are, in fact, complex, and there are many deep-seated reasons behind where we are right now.)
There were a few key points that came out of the panel above and from related discussions at the symposium.
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| Vibrating H2 molecule, electron density from DFT, by Dr. Or Cohen. |
While technically the funds don't go away at the end of September, this kind of underspending raises the possibility of a pocket rescission. OMB and the executive branch have been pushing for massive cuts to the agency; Congress has disagreed. It sure looks like all the "see, don't worry, Congress didn't allow big cuts to the NSF" palliative statements don't hold up very well to scrutiny, if the majority party is content to just give up Article I power to the executive branch.
In this period of complete flood-the-zone craziness, the mainstream news media seemingly doesn't have the bandwidth or interest to report on this; they seem to have judged that it's too obscure, it doesn't play in Peoria, the public doesn't really care. This kind of disruption will have ripple effects that last for many years and affect US scientific and economic competitiveness, and it's happening without much notice.
This week's news about an agreement between NIH and DOD to funnel NIH funds for infectious disease to DOD (or, in the official statement, to work together on projects of mutual interest), is at least getting some public attention. Agencies agreeing to pass around at minimum hundreds of millions of dollars outside congressional oversight or what the appropriations acts say is another example of an Article I crisis, when the majority party basically hands over what are supposed to be congressional powers to executive branch.
(An additional sciencey blog post coming soon!)
This past week was a genuinely horrific reminder of the importance of lab safety, especially in the realm of hazardous chemicals.
First, a graduate student at Hokkaido University was killed due to some kind of large-scale exposure to hydrofluoric acid. For those who don't know, HF is used at some rate in semiconductor-related work, because it's a way to etch SiO\(_2\) from silicon surfaces and leave a hydrogen-terminated surface. (Usually this is done using buffered oxide etch, which is less concentrated than the pure acid but still must be handled with great care and appropriate personal protective equipment.) Accidental exposure to small amounts of HF is not always immediately obvious, because it is not that aggressive in damaging human skin (unlike, say, nitric or sulfuric acid). Rather, it attacks the calcium in bones (as well as screwing up many other biological processes). The topical treatment is calcium gluconate gel, which can help by being a much more readily accessible source of calcium ions to bind with the fluoride ions. There are no real details out yet about how someone had a massive amount of HF splash on their head/face, but that sure sounds like a terrible case of poor storage and handling practices.
Then it came out that this past Wednesday a doctoral student at MIT had been exposed to dimethyl mercury. Here is a reddit discussion thread in r/mit, and here is another one on r/chemistry. Apologies for the reddit links, but there doesn't seem to be any news reporting about this yet. From the MIT announcement in those threads, it was in building 18, and decontamination of the space is ongoing. Any scientist of my generation knows about dimethylmercury because of the horrifying death of Dartmouth chemistry professor Karen Wetterhahn in 1997. She was exposed to tiny drops of this stuff, which diffused through her latex gloves (which she did not realize at the time). Prior to her death, people still occasionally used dimethylmercury as a standard in NMR measurements. Organic mercury compounds are widely recognized as incredibly dangerous because tiny amounts can lead to mercury crossing the blood-brain barrier, leading to terrible neurological systems and death. Once mercury is into organic tissues, it is very difficult to chelate the metal ions. Again, there is a shortage of official information about this incident, but MIT's announcement made it clear that any synthesis or use of this compound is not permitted and was unauthorized.
Update: the latest from MIT’s emergency response page raises the possibility that there may not have been any exposure or dimethylmercury present. Fingers crossed that this turns out to be a false alarm.
Update 2: The always excellent Derek Lowe with a further discussion of what seems now to have (thankfully, hopefully) been a false alarm.
To students reading this: PLEASE be careful in the lab. Know the hazards of what you're doing, and use appropriate procedures and protective equipment. If you ever have questions about safety, for goodness' sake please ask. Your PI and your environmental health and safety team would far rather have you ask questions and be cautious then to do something dangerous. No PI should ever make students feel like thinking about safety is unnecessary or overly cautious, and no PI should ever be hesitant about supplying or letting students purchase PPE.
| After Fig. 2b from here |
In case you weren't aware, in addition to the OMB proposed rule changes which just concluded their public comment period, the NSF has put forward proposed changes in their proposal procedures for public comment, and the last day for feedback is August 24. The proposal and award policies and procedures guide (PAPPG) is to be replaced with the revised document called the "Guide for Financial Assistance" (GFA).
The proposed revised document is here: https://www.regulations.gov/document/NSF-2026-OTR-0001-0003
The place to file a comment is here: https://www.regulations.gov/docket/NSF-2026-OTR-0001/document?withinCommentPeriod=true
The place read already-filed comments is here: https://www.regulations.gov/docket/NSF-2026-OTR-0001/comments
The Federation of American Societies for Experimental Biology has a brief summary of the proposed changes here. There are a number of (IMO) problematic issues with the would-be revisions, not the least of which is they presumptively assume that the OMB changes are going into effect, including the very controversial ones that would allow termination of awards at any time, for any reason (including not aligning with presidential priorities), with no appeal. It's a good idea to be aware of what's being proposed and to take advantage of the opportunity to provide feedback.
Update: The APS has also put together a guide to the proposed changes.
Speaking of feedback, the American Physical Society is doing a broad survey (beyond just physicists) asking for input about up to three things that people think the NSF does well and up to three things that the NSF should do differently. It's open to everyone, and the response spaces are brief (500 char ea.). Again, if this is something that matters to you, I encourage you to contribute - it's quick.
Yesterday I attended the 40th annual summer research colloquium of the Smalley-Curl Institute at Rice, a fun internal conference that provides a great opportunity for undergrads (including visitors), graduate students, and a few postdocs to present their work. The keynote speaker was our EVPR, Prof. David Sholl, who gave a very informative talk about reproducibility in the chemical engineering/materials literature. We hear a lot these days about crises of reproducibility in scientific research, and Prof. Sholl rightly points out that in some fields the expectation of reproducible results is high - no one would spend $1B on a chemical engineering plant if they weren't very sure that the catalytic processes were going to work as expected at scale. Keys to reproducibility include, unsurprisingly, repeated results and independent replication. One metaresult that was interesting is this paper, looking at the literature on metal-organic frameworks and how often there are published replications of syntheses; not as often as you would think or want!
A truly surprising (to me, anyway) result is this one. The Brunauer–Emmett–Teller (BET) (yes, that Teller) method is a long-established technique that uses gas adsorption measurements to infer the surface area of porous materials. Many research groups were given identical raw adsorption isotherms and asked to calculate the specific surface areas, resulting in a surprisingly large spread of results (Fig 1 of the paper). Clearly not everyone had the same analysis procedures even for a technique developed in the 1930s!
Some take-away lessons from this are encapsulated here, in an article titled "Five easy ways to make your research more reproducible". Good stuff. The talk raised a number of questions relevant to our present era of huge enthusiasm about AI-based materials research and "self-driving" labs. If the AI models are all trained on the literature, and the literature is not representative of complete and reproducible procedures, that's a problem.
One personal anecdote about reproducibility and its challenges in materials synthesis. Twenty years ago (!), I was working with a colleague who had a postdoc who was synthesizing Fe3O4 (magnetite) nanoparticles via wet chemistry methods (see here). We did some fun electronic transport experiments bridging very closely spaced electrodes with such nanoparticles, and we saw some very dramatic hysteretic response kick in as \(T\) was reduced below about 120 K. That's the temperature of the Verwey transition in magnetite, where the material enters a more insulating low temperature phase. Basically all of the devices we made with that batch of nanoparticles showed this phenomenon. Then the postdoc took up a faculty position and a senior grad student came in and took over the synthesis, and for several months, subsequent batches of nanoparticles just didn't seem to show the effect. The key issue is oxygen stoichiometry. Get a little oxygen rich, and you form nanoparticles that include some \(\gamma\)-Fe2O3, which doesn't have the Verwey physics and in nanoparticle form looks really similar in x-ray diffraction to the desired magnetite. Anyway, we started working with a collaborator who could grow epitaxial Fe3O4 films, and in those devices the electronic effect was there all the time. All this led to this publication and subsequent papers, and I still think it's a cool set of results about a nonequilibrium transition in a correlated material. In the end, after several months the chemistry grad student did get back to making nanoparticle batches that showed the transition. It turns out that at some point he had changed the length of a piece of tubing in the gas manifold, and unexpectedly that had altered the reaction kinetics just a little. Changing it back got the synthesis to be reliable again. This is an example of how finicky materials synthesis can be!
I think it's safe to say that most people who've considered the issue think that a doctoral degree in the sciences and engineering in the US often takes too long.
How long? According to the latest data (see here, Table 1-12), the median time to degree in the physical sciences, for example, is 5.7 years after starting the program, while in all of engineering it's 5.3 years.
Too long for what? Well, life, basically. Any decision to go to grad school is inherently a trade-off with opportunity costs. Graduate stipends remain low compared to expected wages in entry-level (bachelors degree-qualified) positions in the sciences and engineering in industry. The long duration of doctoral programs is certainly a powerful disincentive for many who might be interested but are under financial pressures. Family considerations are also a major factor. From the perspective of basically any career path, thanks to the time value of money and ideas of seniority, it's better to get going earlier if you have the qualifications for the particular job. Companies would rather hire younger (cheaper) people.
So, there are already strong reasons to think about shortening doctoral programs. Now, with the proposed change in duration of status of student visas (rule here, with plenty of editorializing; legal challenges very likely forthcoming in September) to four years, there is additional pressure.
Why do US programs take so long? Don't they give PhDs in three years in the UK and Europe? In the UK and Europe, a student enters a doctoral program after already pursuing and receiving a masters degree, with grad level coursework taking place there. Thus they go directly into research. In the US, in contrast, it is far more common for students to go directly into the doctoral program. Likewise, in the US, it is far more common for funding for students to go through PI-written research proposals, while in the UK, the students come funded, so to speak.
This is certainly a very interesting pilot program. There are rumors that the DOE Genesis Mission is going to put something extremely similar in place as well. The implementation details will be enormously important. (For example: Who is eligible? Who handles the coordination between industry and the university - that is, who does the match-making and how? At the department-company level and at the particular academic/industrial advisor level? How will intellectual property be handled? Publications? Project design? If there are economic challenges, how committed are the companies?) Given that this is a form of NSF fellowship, it seems highly likely that it will only be open to US citizens and permanent residents. Obviously, not every discipline is well-suited to this, in terms of there being a ready supply of companies set to buy in. Still, it is absolutely worth seeing how this works.
Update: Thanks to one of my colleagues for pointing out the fine print, which is here. In brief, as expected this is only open to US citizens and permanent residents. No indirect costs allowed. There is a $16K cost-of-education piece that looks like a substitute for grad tuition. The intellectual property issues have to be ironed out between the university and the company before the start. Perhaps not unexpectedly, this is most likely to work well for programs and PIs who already have close collaborations with particular companies. Engineering disciplines are most likely to fit well here, it seems, while basic research farther away from applications will have more challenges. (Question: will finance companies or AI materials companies be interested in supporting theorist/computational scientists through this mechanism?)
First, some science, clearing out a number of papers and articles that I've been collecting for some time in my far-too-numerous browser tabs:
| A 4-channel wavelength division multiplexer made from etched Si3N4, from this paper. |
When I wrote this post last month, I really did not want it to be first in a series.
The inciting incident to write that post was a news article in Science reporting that there have been draconian ~ 30% cuts in present fiscal year budgets within the NSF. Program officers were instructed to keep this confidential and not talk about it with PIs. The rumor was that this funding would go to support the TIP directorate and its activities, particularly the "X-Labs".
Now Dan Garisto has broken this story in Nature. For some, this is behind a paywall, so let me hit the highlights.